Madison, Wisconsin, a place known for its superb selection of craft beverages, for having Wisconsin’s Best Cheese Curds, and, most importantly, for hosting the 2022 annual international conference on Intelligent Systems for Molecular Biology (ISMB). Fortunately, we (Lewis and Tobias) got to attend this year’s ISMB and get a taste of Madison. The 2022 conference is the 30th ISMB conference and has grown to become the world’s largest bioinformatics/computational biology conference with nearly 600 presented talks. We therefore got to hear a wide range of different and interesting talks.
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Antibodies as Drugs: Keystone Symposia
Between the 27th April and 1st of May, I was very fortunate to be able attend the Antibodies as Drugs Keystone Symposium and give my first conference talk internationally, in which I spoke about the methods our group has developed for using structure to make predictions about where an antibody binds relative to other antibodies. This included paratyping [1], Ab-Ligity [2] and most recently SPACE [3].
I will preface this by saying that lots of the work people spoke about was unpublished, which was so exciting, but makes for a difficult blog post to write. To avoid any possibility of putting my foot in my mouth I will keep the science very surface level. The conference was held at the Keystone resort in Colorado, and the science combined with a kind of landscape I have never experienced before made for an extremely cool experience. This meeting was originally combined with a protein design meeting, and the two were split by COVID – this meant that in-silico methods were the minority in the program, but I didn’t mind that as the computational work that was presented was quite diverse so it was definitely a good representation of the field still. I also really enjoyed the large number of infectious disease talks in which we got a good range of the major human pathogens – ebolaviruses, SARS-CoV-2 of course, dengue, hantaviruses, metapneumovirus, HIV, TB and malaria all featured. The bispecific session was another highlight for me. The conference was very well organised and I liked how we were all asked to share a fun fact about ourselves – one speaker shared that he is a Christmas tree farmer in his spare time (I won’t share his name in case he is keeping that under wraps). That made me reconsider how fun I can truly consider myself…
Without turning this into a travel blog, I also want to add that Keystone was insanely beautiful and make you look at some pics I got.
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