Tag Archives: conference

Roche Continents 2024

This July I had the opportunity to be part of the Roche Continents programme [1]. The programme was organised by Roche and LUMA Arles and took place in the beautiful city of Arles in the south of France. Together with 40 students from various disciplines and European universities we discussed and explored the connection between arts, science, and sustainability. The theme of the week was resourcefulness.  

For students considering applying to Roche Continents next year, I’d like to offer some insights on what to expect, as well as share a few of my personal highlights from the experience. 

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Experience at the Computational Chemistry Gordon Research Conference

This past July I had the absolute delight of attending the Computational Chemistry Gordon Research Seminar and Conference all the way in Portland, Maine. It was my first Gordon experience, which was invigorating seven-day experience with lots of great science and meeting great people!

Since pictures and videos are not allowed at GRCs as they support the presentation of unpublished results, I’ll talk more generally about the conference as a whole and the general science themes related to my work.

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Conference Summary: AIRR Community Meeting VII – Learnings and Perspectives

At the start of June, we (Lewis and Benjie) attended the AIRR Community meeting in beautiful and sunny Porto, Portugal. This meeting was focused on collecting and analysing adaptive immune receptor repertoires. This comprised of two rivalling factions at the conference: the antibody (Ab) people or the T cell antigen receptor (TCR) people. The split was nearly fifty-fifty between these two topics throughout the conference. Overall, the conference was a fairly comfortable size, with approximately a hundred people in attendance, making it easy to visit all of the posters and talk with many people in your area, without feeling too niche. There was a wide variety of content formats throughout the conference including posters, scientific talks, lightning talks, software demos, and hands-on tutorials. In the following section, we highlight some of our favourite sessions to give a flavour of what this meeting entails.

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Conference summary: Generative AI in Life Science

This year I attended the second edition of Generative AI in Life Science (GenLife – https://genlife.dk/) and it was an enriching experience that I thoroughly enjoyed. Held in Copenhagen, the event brought together researchers from different areas of AI applied to the life sciences and provided a fantastic platform for networking, learning and sharing ideas. The programme included a mix of long and short talks from experts in the field, but also had a significant presence of emerging PIs, making the conference a perfect place to discover emerging groups in the field. Here I have collected some highlights of the talks I have enjoyed the most at the conference.

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RSC Fragments 2024

I attended RSC Fragments 2024 (Hinxton, 4–5 March 2024), a conference dedicated to fragment-based drug discovery. The various talks were really good, because they gave overviews of projects involving teams across long stretches of time. As a result there were no slides discussing wet lab protocol optimisations and not a single Western blot was seen. The focus was primarily either illustrating a discovery platform or recounting a declassified campaign. The latter were interesting, although I’d admit I wish there had been more talk of organic chemistry —there was not a single moan/gloat about a yield. This top-down focus was nice as topics kept overlapping, namely:

  • Target choice,
  • covalents,
  • molecular glues,
  • whether to escape Flatland,
  • thermodynamics, and
  • cryptic pockets
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Festival of Biologics 2022 – November 2-4 Basel, Switzerland

In November I attended the Festival of Biologics (FoB) 2022 conference in Basel, Switzerland. Originally a set of different conferences (now called agendas) that has merged into a single conference, FoB focuses on anything related to biologics. One of the agendas is an antibody specific agenda, derived from the former European Antibody Congress. This year the antibodies agenda had more than 100 talks across multiple tracks, covering many different aspects of using antibodies as therapeutics, making it an exciting conference for an antibody enthusiast. However, while FoB does include talks on machine learning and bioinformatics, most are focused solely on experimental work. Another drawback is that the majority of the talks are by industry, with the few academic speakers almost all also representing a company. This meant that of the few talks about computational methods and tools for protein design, most felt more like a commercial rather than a research presentation. Nonetheless, FoB is still an interesting conference to attend when you are working on applied research for antibody therapeutics. It is an amazing opportunity to hear about which antibody specific problems companies are trying to overcome, which are deemed solved and which are the future problems to solve.

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Thinking of going to a conference

As so many members of the group have never attended an in-person conference, I thought it might be worth answering the question “why do people attend conferences?”

First- up, we should remember that flying around the world is not a zero cost to the planet, so all of us lucky enough to be able to travel should think hard every time before we choose to do so.

This means it’s really important to make sure that we know why we are going to any conference and maximise the benefits from attendance. Below are a few things to think about in terms of why you attend a conference and what to do when you are there, but this is definitely not a complete list, more a starter for four.

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Vaccines and vino

Recently, I was fortunate enough to attend and present at GSK’s PhD and Postdoc workshop in Siena, Italy. The workshop spanned two days and I had a brilliant time there – Siena itself is beautiful, I ate fantastic food, and I learnt a huge amount about all stages of vaccine production.

Unfortunately, due to confidentiality, I can’t go into great detail about others’ current research, however I have provided a short overview of the five main areas the workshop focused on below.

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Antibody Engineering and Therapeutics Conference

I was invited to speak at the Antibody Engineering and Therapeutics Conference (presenting mine and Matt’s recently published epitope profiling paper), in San Diego (December 12th – 16th). Unfortunately, the pandemic had other ideas so I decided not to travel but luckily the conference was hybrid. 

The conference included 1 day of pre-conference workshops and 4 days of presentations from academic and industry, with livestreaming of the initial keynotes (including one from Charlotte). Remaining talks were recorded and made available after the conference. I’ve highlighted a few of my favourite talks and conference themes, with links to papers where available.

Naturally, a lot of the presented research related to covid-19. I was speaking in the ‘Antibody Repertoires and Covid-19’ session, where there were interesting presentations from Professor Eline Luning Prak from the University of Pennsylvania and Elaine Chen from Vanderbilt University analysing antibody responses in covid-recovered individuals, and comparing vaccine responses in covid-recovered vs covid-naiive individuals. Other talks around SARS-CoV-2 vaccines included Dr Laura Walker from Adimab/Adagio Therapeutics comparing BCR repertoire responses to different types of vaccinations, and the effect of using different booster types.

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Highlights from the European Antibody Congress 2021

Last month, I was fortunate enough to be able to attend (in person!) and present at the Festival of Biologics European Antibody Congress (9-11 November, 2021) in Basel, Switzerland. The Festival of Biologics is an annual conference, which brings together researchers from industry and academia. It was an excellent opportunity to learn about exciting research and meet people working in the antibody development field.

Here are some of my highlights from the European Antibody Congress, with a focus on antibody design and engineering:

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